Research Papers
  1. Chacon-Barahona J.A., MacKeigan J.P., Lanning N.J. Unique Metabolic Contexts Sensitize Cancer Cells and Discriminate between Glycolytic Tumor Types. Cancers. 2023, 14(4), 1158.
  2. Chacon-Barahona, J.A.; Salladay-Perez, I.A.; Lanning, N.J. Lung Adenocarcinoma Transcriptomic Analysis Predicts Adenylate Kinase Signatures Contributing to Tumor Progression and Negative Patient Prognosis. Metabolites 2021, 11, 859. PMID: 34940617.
  3. Lanning, NJ, VanOpstall C, Goodall ML, MacKeigan JP, Looyenga BD. LRRK2 Deficiency impairs trans-Golgi to lysosome trafficking and endocytic cargo degradation in human renal proximal tubule epithelial cells. Am J Physiol Renal Physiol. 2018 Aug 8. PMID: 30089035.
  4. Lanning NJ, Castle JP, Singh SJ, Leon AN, Tovar EA, Sanghera A, MacKeigan JP, Filipp FV, Graveel CR. Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities. Cancer & Metabolism. 2017; 5:6. eCollection 2017 PMID: 28852500.
  5. Sasi NK, Bhutkar A, Lanning NJ, MacKeigan JP, Weinreich M. DKK Promotes Tumor Chemoresistance and Survival via Multiple Pathways. Neoplasia. 2017; 19)5):439-450. PMID: 28448802
  6. Lanning NJ, Looyenga BD, Kauffman AL, Niemi NM, Sudderth J, DeBerardinis RJ MacKeigan JP.  A mitochondrial RNAi screen defines cellular bioenergetics determinants and identifies an adenylate kinase as a key regulator of ATP levels. Cell Reports. 2014; 8;7(3):907-17. PMID: 24767988
  7. Niemi NM, Sacoman JL, Westrate LM, Gaither LA, Lanning NJ, Martin KR, MacKeigan JP. The pseudophosphatase MK-STYX physically and genetically interacts with the mitochondrial phosphatase PTPMT1. PLoS One. 2014; 9(4):e93896. PMID: 24709986
  8. Su HW, Lanning NJ, Morris DL, Argetsinger LS, Lumeng CN, Carter-Su C.  Phosphorylation of the adaptor protein SH2B1β regulates its ability to enhance growth hormone (GH)-dependent macrophage motility. J Cell Sci.  2013; 126(8):1733-43. PMID: 23444381
  9. Niemi NM, Lanning NJ, Westrate LM, MacKeigan JP.  Downregulation of the mitochondrial phosphatase PTPMT1 is sufficient to promote cancer cell death. PLoS One. 2013; 8(1):e53803. PMID: 23326511
  10. Lanning NJ, Su HW, Argetsinger LS, Carter-Su C. Identification of SH2B1β as a focal adhesion protein that regulates focal adhesion size and number. J Cell Sci. 2011; 124(18):3095-105. PMID: 21878491
  11. Cui TX, Lin G, LaPensee CR, Calinescu AA, Rathore M, Streeter C, Piwien-Pilipuk G, Lanning N, Jin H, Carter-Su C, Schwartz J.  C/EBPβ mediates growth hormone-regulated expression of multiple target genes. Mol Endocrinol. 2011; 25(4):681-93. PMID: 21292824
  12. Niemi NM, Lanning NJ, Klomp JA, Tait SW, Xu Y, Dykema KJ, Murphy LO, Gaither LA, Xu HE, Furge KA, Green DR, MacKeigan JP.  MK-STYX, a catalytically inactive phosphatase regulating mitochondrially dependent apoptosis. Mol Cell Biol. 2011; 31(7):1357-68.  PMID 21262771
  13. Jin H*, Lanning NJ*, Carter-Su C. JAK2, But Not Src Family Kinases, Is Required for STAT, ERK and Akt Signaling in Response to Growth Hormone in Preadipocytes and Hepatoma Cells. Mol. Endocrinol. 2008; 22(8) 1825-41.  PMID: 18499741 *These authors contributed equally to this work.
  14. Zhang YW, Su Y, Lanning N, Swiatek PJ, Bronson RT, Sigler R, Martin RW, Vande Woude GF. Targeted disruption of Mig-6 in the mouse genome leads to early onset degenerative joint disease. Proc. Natl. Acad. Sci. U S A. 2005; 102(33):11740-5.  PMID: 16087873
  15. Zhang YW, Su Y, Lanning N, Gustafson M, Shinomiya N, Zhao P, Cao B, Tsarfaty G, Wang LM, Hay R, Vande Woude GF. Enhanced growth of human met-expressing xenografts in a new strain of immunocompromised mice transgenic for human hepatocyte growth factor/scatter factor. Oncogene. 2005; 24(1):101-6. PMID: 15531925
Reviews
  1. Castellanos E, Lanning NJ. Phosphorylation of OXPHOS Machinery Subunits: Functional Implications in Cell Biology and Disease. Yale J. Biol. Med.​ 2019. 92(3):523-531. PMID: 31543713
  2. Fogg VC, Lanning NJ, MacKeigan JP. Mitochondria in cancer: at the crossroads of life and death. Chin. J. Cancer. 2011; 30(8):526-39 PMID: 2180160
  3. Lanning NJ, Carter-Su C. Recent advances in growth hormone signaling. Rev. Endocr. Metab. Disord. 2006. 7(4):225-35. PMID: 17308965​
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